Background: Calcium sodium phosphosilicate is a recently introduced desensitizing agent which acts by occluding the dentinal tubules and also resists acid decalcification. This study was designed to assess the efficacy of a new toothpaste containing 5% calcium sodium phosphosilicate for the treatment of dentinal hypersensitivity and also compare it with 5% potassium nitrate.

Materials and Methods: Sixty patients with the chief complaint of dentinal hypersensitivity were enrolled and randomly divided into two groups. The visual analog scale (VAS) scores were taken for water and air stimuli at baseline, 3 weeks after usage of the respective toothpaste, and 3 weeks after discontinuation of the respective toothpaste.

Results: Both the groups showed reduction in hypersensitivity scores at 3 weeks and 6 weeks for air stimulus and cold water. The calcium sodium phosphosilicate group, however, showed significantly reduction in hypersensitivity compared to the potassium nitrate group at any time point for both measures of hypersensitivity.

Conclusion: The 5% calcium sodium phosphosilicate group showed immense reduction in dentinal hypersensitivity symptoms. The 5% calcium sodium phosphosilicate showed prolonged effects even after discontinuation as compared to 5% potassium nitrate, due to its dentinal tubular occlusion property.

Context: Dentinal hypersensitivity (DH) is a commonly encountered dental problem. Several products are used in its management with varying results. There is a need for a material that chemically reacts with dentin, physically occludes dentinal tubules, and adheres intimately to them to reduce the possibility of recurrence. One such material is calcium sodium phosphosilicate (NovaMin®).

Aim: To evaluate the efficacy of a dentifrice containing 5% calcium sodium phosphosilicate (NovaMin® SHY-NM™) compared with a placebo dentifrice for the relief of dentinal hypersensitivity.

Settings and Design: Outpatients visiting the Department of Periodontics, Yenepoya Dental College, with dentinal hypersensitivity were considered eligible for this case-control clinical trial after providing informed consent.

Materials and Methods: Thirty patients with at least two sensitive teeth and a Visual Analogue Scale (VAS) score of >3 cm following air-blast stimulation qualified for the study. Participants were divided into a test group receiving SHY-NM™ toothpaste containing 5% calcium sodium phosphosilicate and a control group receiving Pepsodent toothpaste without a desensitizing agent, with 15 participants in each group. Dentinal hypersensitivity was assessed using cold-water and air-blast stimulation at baseline, the 6th week, and the 8th week using VAS. Statistical analysis was performed using the unpaired t-test and repeated-measures ANOVA.

Results: The dentifrice containing 5% NovaMin® produced a significant reduction in dentinal hypersensitivity at the 6th and 8th weeks of use compared with the placebo dentifrice.

Conclusion: A dentifrice containing NovaMin® significantly reduced dentinal hypersensitivity compared with a placebo dentifrice.

Background: Dentine hypersensitivity is a common complaint among dental patients. Recently, a novel stabilized calcium sucrose phosphate dentifrice was introduced that offers a desensitizing benefit. The primary aim of this study was to compare the in vivo efficacy of this novel dentifrice with Calcium sodium phosphosilicate and a non-desensitizing dentifrice, on dentin hypersensitivity in a four-week period.

Methods: Sixty volunteers with tooth sensitivity were recruited, and a double-blind, randomized, parallel, controlled clinical trial was conducted in a hospital setting. Clinical evaluation for dentin hypersensitivity by 0-10 VAS score was done using air blast, and cold water methods. Following baseline measures, subjects were randomly divided into three groups and treated as follows: Group A–dentifrice containing calcium sodium phosphosilicate (Novamin); Group B–dentifrice containing Calcium sucrose phosphate; and Group C—dentifrice containing no desensitizing ingredients. Clinical evaluations were repeated after two and four weeks of product use.

Statistical analysis used: Mean VAS scores were compared among groups at different time points (baseline, and 2 and 4 weeks) and among groups at each time point using one-way analysis of variance.

Results: Compared to baseline, there was a clinically significant decrease in dentin hypersensitivity in Groups A and B following four weeks use of the dentifrices containing calcium sodium phosphosilicate and calcium sucrose phosphate, respectively. The Group A dentrifice, however, was found to be significantly better in reducing the VAS score read more.